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For example, genistein inhibits DNMT, promoting the expression of the anti-fibrotic miRNA miR-29, while EGCG (epigallocatechin gallate) inhibits HDAC, thereby upregulating miR-15 expression, which prevents apoptosis (Wang et al., 2021

ALCAR, thanks to its acetyl group, can cross the blood-brain barrier and additionally supports acetylcholine production, making it the preferred form for cognitive and brain-health goals

(5) Reverse NET transport and hypertensive crisis: Increased cytoplasmic NE and transporter phosphorylation drive NET-mediated reverse transport, resulting in massive non-exocytotic NE release into the synaptic cleft and a marked rise in blood pressure

This is a classic hormonal feedback loop that results directly in fluid retention

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